Malaria

Fièvre jaune, paludisme... Ne gâchez pas vos vacances

Selon la destination choisie, quelques précautions s'imposent pour que les vacances ne virent pas au cauchemar. Et plus que des précautions, quand on parle de vaccins, c'est même une obligation.
Ainsi, pour se rendre dans certaines régions d'Afrique, voire plus près de nous, en Guyane, d'après l'Institut Pasteur, il est indispensable de se faire vacciner contre la fièvre jaune au moins dix jours avant le départ.
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First malaria vaccine moves closer to approval

European drug regulators just gave a major lift to the world’s first malaria vaccine.
 
The European Medicine Agency on Friday adopted a positive scientific opinion for the drug — potentially paving the way for it to be recommended for approval by the World Health Organization later this year.
 
 
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Un vaccin contre le paludisme en gestation au Gabon

Le Centre de recherches médicales de Lambaréné (CERMEL) au Gabon, une unité qui focalise ses recherches sur les maladies infectieuses tropicales, vient de développer avec succès un candidat-vaccin anti-paludisme.

Baptisé "RTS, S", ce candidat-vaccin a été conçu par le laboratoire Belge GSK dans les années 90 et ses premières études ou tests cliniques ont commencé en 1995 chez les adultes aux Etats-Unis et en Europe.

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Malaria morbidity and mortality in Ebola-aff ected countries caused by decreased health-care capacity, and the potential eff ect of mitigation strategies: a modelling analysis

Summary
 
Background The ongoing Ebola epidemic in parts of west Africa largely overwhelmed health-care systems in 2014, making adequate care for malaria impossible and threatening the gains in malaria control achieved over the past decade. We quantified this additional indirect burden of Ebola virus disease.
 
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Ebola Linked to Rise in Malaria Deaths in Guinea

(HealthDay News) -- The Ebola epidemic in West Africa appears to have led to an increase in malaria deaths last year, a new study finds.
 
Research in Guinea, one of the countries hardest hit by the Ebola epidemic, indicates an extra 74,000 cases of malaria went untreated in 2014, compared to previous years. As a result, deaths associated with malaria (a mosquito-borne disease) also rose and will likely exceed Ebola deaths in Guinea, researchers reported June 23 in The Lancet Infectious Diseases.
 
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World’s first malaria vaccine shows promising results in human trials

For the first time ever, a malaria vaccine candidate has reached phase 3 of clinical testing. With just one phase of testing left to complete, this is the closest researchers have ever come to finding a successful vaccine for the disease.
 
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Ivory Coast attains universal insecticidal net coverage

Ivory Coast recently achieved improved protection against malaria thanks to nearly universal coverage of the nation’s population with 13 million insecticidal mosquito nets.
 
The $55 million Global Fund campaign began last year, and will soon end in the county’s capital, Abidjan. Approximately 18,500 people volunteered for the distribution, which received expertise and logistical support from the World Health Organization, UNICEF and CARE.
 
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Diseases of Poverty: Shrinking the Map on Malaria, NTDs

Less than a decade ago, the city of Dajabón in the Dominican Republic (DR) shouldered a high burden of malaria, reporting 989 cases in 2007 alone. That number has dwindled over the years, due in large part to support from partners, better diagnostic tools and more targeted interventions. In 2013, only 60 cases of malaria were reported. What’s most exciting is that this kind of progress is not limited to just Dajabón or the DR at large.
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First malaria vaccine shows promise despite efficacy drop-off

Final phase 3 trial results of a malaria vaccine designed to knock down the high burden of disease in African children showed that it can prevent a substantial number of infections, but the length of protection wasn't as long as hoped.
 
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Malaria: la recherche d’un vaccin progresse

Avec 200 millions de personnes infectées et 600 000 morts par année, essentiellement chez les enfants africains, la malaria (ou paludisme) est une des maladies infectieuses les plus meurtrières du monde. Des mesures préventives comme l’utilisation de moustiquaires imprégnées d’insecticides ont certes permis de faire chuter la mortalité de près de 50% depuis 2000, mais il n’existe toujours pas de vaccin efficace contre la maladie. «La malaria est causée par un parasite du nom de Plasmodium transmis lors de piqûres de moustiques.

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