Hepatitis B

World Immunization Week: A boy in a remote Ethiopian village gets his first shots

Nyabel Both lives in a remote village in the Gambella region of Ethiopia, where common childhood diseases like malaria, tuberculosis and diarrhea are a constant threat.
 
Yet Nyabel has managed something wonderful: Her one-year-old son has been vaccinated for measles, polio, tuberculosis, diphtheria, tetanus, pertussis, Hepatitis B and Haemophilus influenzae—in other words, she has fully immunized her child.
 
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Type 2 diabetes does not affect hepatitis B vaccination

Type 2 diabetes does not negatively affect the immune response to hepatitis B vaccine, an international trial suggests.
 
Andrew Trofa, MD, GlaxoSmithKline Biologicals and colleagues evaluated the three-dose hepatitis B vaccine in 512 adult men and women with type 2 diabetes. None of the participants had any history of hepatitis B infection or vaccination.
 
256 control participants were also included, with all recruits divided into eight subgroups based on age and BMI. 
 
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J&J partners with startup for DNA vaccine, hand-held device to treat HBV in $85M+ deal

Janssen Pharmaceuticals has paired up with Ichor Medical Systems to develop and market DNA-based vaccine products to treat chronic hepatitis B (HBV). The partners will use the startup's TriGrid electroporation technology for clinical administration of a DNA vaccine.
 
 
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La confiance des médecins dans la vaccination, point clef pour l'application des recommandations vaccinales

Ces dernières années, un accroissement préoccupant d'opinions défavorables à la vaccination a été constaté dans la population générale en France. Plusieurs controverses ont eu lieu depuis la fin des années 1990 :
 
  • maladies neurodégénératives et vaccination contre l'hépatite B,
  • remise en cause de la vaccination contre la grippe pandémique A(H1N1)pdm09,
  • plaintes pénales à propos d'événements indésirables attribués à la vaccination contre les papillomavirus,
  • mise en cause de l'aluminium présent dans certains vaccins.
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HBV: React Before the Virus Does

Let me begin by paraphrasing Santayana: "Those who cannot recognize the past are condemned to repeat it."
 
I refer specifically to the importance of recognizing past infection with the hepatitis B virus (HBV) to forestall reactivation of clinically significant viral hepatitis during immunosuppressive therapy.
 
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Immunization coverage

Key facts
 
  • Immunization prevents illness, disability and death from vaccine-preventable diseases including cervical cancer, diphtheria, hepatitis B, measles, mumps, pertussis, pneumonia, polio, rotavirus diarrhoea, rubella and tetanus.
  • Global vaccination coverage is holding steady.
  • Immunization currently averts an estimated 2 to 3 million deaths every year.
  • But an estimated 21.8 million infants worldwide are still missing out on basic vaccines.
 
Overview
 
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Tensions d’approvisionnement des vaccins contre la coqueluche : adaptation de la stratégie vaccinale

Le Haut Conseil de santé publique (HCSP) vient de publier un avis sur l'adaptation de la stratégie vaccinale face aux difficultés d'approvisionnement des vaccins combinés contenant la valence coqueluche (avis du 25 février 2015).
 
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Protection Without a Vaccine

Last month, a team of scientists announced what could prove to be an enormous step forward in the fight against H.I.V.
 
Scientists at Scripps Research Institute said they had developed an artificial antibody that, once in the blood, grabbed hold of the virus and inactivated it. The molecule can eliminate H.I.V. from infected monkeys and protect them from future infections.
 
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At long last, Sanofi launches low-cost pentavalent in India

It's been a long road for Shan5, the low-cost pentavalent from Sanofi-owned Shantha Biotechnics. Now, after manufacturing tie-ups four years ago cost the company a $340 million contract to supply the vaccine, it's finally rolling out the product in India.
 
With the launch, 27 million babies born annually in India will now have access to the 5-in-1 shot, which protects children against diphtheria, tetanus, pertussis, Hib and hepatitis B, according to Shantha CEO Harish Iyer.
 
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FDA clears syringe that prevents needlestick injuries

Exton, PA's West Pharmaceutical Services just announced that the FDA has given it 510(k) clearance for the NovaGuard Staked-needle Automatic safety system, as the push to avoid needlestick injuries gathers momentum.
 
The company says that the device shields the syringe's exposed needle after it has been activated and contains a tamper-evident safety mechanism to prevent early activation of the device.
 
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