August 19, 2013 -- Researchers from the Salk Institute announced on Wednesday that they have discovered the mechanism viruses like West Nile and dengue use to shut down the body’s defense system.
The findings showed a mechanism that a group of viruses use to disarm the host body’s immune response. The viruses activate a class of molecules, called TAM receptors, located on some immune cells by using a substance called phosphatidylserine, which binds to extracellular proteins and activates TAM receptors on immune cells.
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The original study and publication, published in Cell Host and Microbe, is available for free here.