Cholera Vaccine: Reduction to Single Dose May Save Lives

Vaccination campaigns that use a single dose of oral cholera vaccine (OCV) may be able to prevent more deaths than the standard two-dose campaign, according to a modeling study published online August 25 in PLOS Medicine. Such a strategy may be especially important when vaccine supplies are limited or when an outbreak is characterized by complex logistics.

Soudan du Sud : 1200 cas de choléra et déjà 39 morts

Au Soudan du Sud, la situation est plus que jamais préoccupante. A la famine qui menace un tiers des habitants, et aux conflits sanglants qui font rage dans ce nouvel Etat africain, s’ajoute une épidémie de choléra meurtrière.

Cheap vaccines prevent cholera

A cheap oral vaccine has prevented cases of deadly cholera in a huge trial in Bangladesh.
The infection is spread through contaminated food or water and causes diarrhoea and severe dehydration.
More than 260,000 people took part in the study, which showed that the vaccine cut cases by 37% and halved the number of the most serious ones.
Experts welcomed the findings, published in the Lancet, but said it was crucial to tackle poor sanitation.

Nanopatch : 20 000 micro-aiguilles indolores qui vont révolutionner la vaccination

Nous avons à plusieurs reprises évoqué les remarquables progrès de la vaccination depuis deux siècles mais deux autres révolutions médicales, peu connues du grand public, sont en train de bouleverser les perspectives d’utilisation des vaccins : les vaccins oraux et les nanopatchs.

Nepal earthquakes: How medics race to avert a health crisis

Three weeks, two earthquakes. More than 8,000 deaths and 17,000 injuries. Nearly 3 million displaced and more than 4 million people affected.

Nepal was brought tumbling down through a series of disasters beyond its control. The collapse of buildings may have ceased -- for now -- but the lives of Nepal's residents remain at risk with the deluge of health consequences now facing them.


Zimbabwe faces potential cholera outbreak

Zimbabwe towns that border Mozambique have reported 14 cholera infections as health officials consider how to handle this health threat more effectively than the 2008-09 epidemic.
Zimbabwe’s worst cholera epidemic took place in its capital of Harare in from 2008-09, killing approximately 4,300 people of the more than 100,000 who were infected.

Cholera Vaccine Succeeds in Rural Haiti

A vaccination campaign that almost didn’t happen was widely effective in reducing transmission of cholera in the midst of an ongoing outbreak of the disease in rural Haiti.
According to a study led by Harvard Medical School researchers at Partners In Health, there were 63 percent fewer cholera cases among the thousands of adults and children who received the cholera vaccine Shanchol than among those who were unvaccinated. The results were published in the March issue of The Lancet Global Health.

PaxVax meets primary endpoints in PhIII cholera vaccine trial

Right now, there is no FDA-approved cholera vaccine for U.S. travelers heading to high-risk countries. A California company hopes to change that soon: On Monday, PaxVax said it planned to submit a Biologics License Application (BLA) for its oral single-dose candidate in mid-2015.

Haïti - Choléra : Campagne de vaccination dans les prisons

Suite à une augmentation drastique des cas de choléra, après une saison des pluies particulièrement active (2,000 cas recensés dans la région métropolitaine de Port-au-Prince entre mi-aout et mi-octobre), le Comité international de la Croix Rouge (CICR), en collaboration avec les autorités haïtiennes, notamment le Ministère de la Justice, vient de lancer une campagne de vaccination pour freiner la propagation du choléra dans les prisons du pays.

Infrastructure woes, lack of funds stymie effort to eradicate cholera in Haiti

Health professionals currently fighting a cholera outbreak in Haiti recently said the country cannot afford to wait 40 years for total eradication of the disease.
The United Nations estimates the earliest cholera could be eradicated is within 10 years, but with today’s funding rate, eradication will take four times as long.
The most recent cholera outbreak in Haiti began in October 2010. Since then, more than 707,000 patients have been diagnosed with cholera, and more than 8,600 people have died from the disease.