Nanopatch : 20 000 micro-aiguilles indolores qui vont révolutionner la vaccination

Nous avons à plusieurs reprises évoqué les remarquables progrès de la vaccination depuis deux siècles mais deux autres révolutions médicales, peu connues du grand public, sont en train de bouleverser les perspectives d’utilisation des vaccins : les vaccins oraux et les nanopatchs.

Zimbabwe faces potential cholera outbreak

Zimbabwe towns that border Mozambique have reported 14 cholera infections as health officials consider how to handle this health threat more effectively than the 2008-09 epidemic.
Zimbabwe’s worst cholera epidemic took place in its capital of Harare in from 2008-09, killing approximately 4,300 people of the more than 100,000 who were infected.

Cholera Vaccine Succeeds in Rural Haiti

A vaccination campaign that almost didn’t happen was widely effective in reducing transmission of cholera in the midst of an ongoing outbreak of the disease in rural Haiti.
According to a study led by Harvard Medical School researchers at Partners In Health, there were 63 percent fewer cholera cases among the thousands of adults and children who received the cholera vaccine Shanchol than among those who were unvaccinated. The results were published in the March issue of The Lancet Global Health.

PaxVax meets primary endpoints in PhIII cholera vaccine trial

Right now, there is no FDA-approved cholera vaccine for U.S. travelers heading to high-risk countries. A California company hopes to change that soon: On Monday, PaxVax said it planned to submit a Biologics License Application (BLA) for its oral single-dose candidate in mid-2015.

Haïti - Choléra : Campagne de vaccination dans les prisons

Suite à une augmentation drastique des cas de choléra, après une saison des pluies particulièrement active (2,000 cas recensés dans la région métropolitaine de Port-au-Prince entre mi-aout et mi-octobre), le Comité international de la Croix Rouge (CICR), en collaboration avec les autorités haïtiennes, notamment le Ministère de la Justice, vient de lancer une campagne de vaccination pour freiner la propagation du choléra dans les prisons du pays.

Infrastructure woes, lack of funds stymie effort to eradicate cholera in Haiti

Health professionals currently fighting a cholera outbreak in Haiti recently said the country cannot afford to wait 40 years for total eradication of the disease.
The United Nations estimates the earliest cholera could be eradicated is within 10 years, but with today’s funding rate, eradication will take four times as long.
The most recent cholera outbreak in Haiti began in October 2010. Since then, more than 707,000 patients have been diagnosed with cholera, and more than 8,600 people have died from the disease.

Merck JV signs on Bangladeshi firms to speed low-cost cholera candidate

When Merck's ($MRK) Indian JV, Hilleman Laboratories, teamed up in June with Swedish biotech Gotovax AB, the plan was to get an affordable cholera vaccine to the developing world. Just a few months out, it's inked a pact to make that happen faster.
Hilleman forged an agreement on Tuesday with Bangladesh-based Incepta Vaccine and the public health research organization ICDDR,B to speed the process of getting the Gotovax candidate through trials to licensing and commercialization.

What's the world's biggest health risk?

Infectious diseases can break out suddenly, almost anywhere in the world, and with devastating impact.
The past week has seen Ebola infecting key medical staff in Sierra Leone, a deadly Middle East virus become airborne and a whole city in China put on lock-down for fear of bubonic plague.
The World Health Organisation (WHO), a UN body that exists to protect and advise the international community about threats such as these, raised concerns in May about the "striking changes in the communicable disease situation".

UNICEF helps tackle cholera in Haiti with sanitation campaign

UNICEF and the Haitian government launched a new campaign this week aimed at improving sanitation facilities in the country to combat the spread of cholera.
The National Sanitation Campaign will target 55 communities in the country, covering approximately 3.8 million people. The “community-led total sanitation” approach encourages leadership at the community level and has been used successfully in the past, according to a UNICEF press release.