U.S. academics test new mouse model for possible Zika vaccine

by FierceBiotechResearch
April 6, 2016

A research team at Washington University School of Medicine has established a new mouse model for testing vaccines and therapeutics that can battle Zika virus after discovering that the mice mimic the way humans are infected. 

The new research, published this week in Cell Host & Microbe, showed that these mice carry high levels of the virus in their brain and spinal cord, consistent with evidence showing that Zika causes neurological defects in human fetuses. 

The researchers also detected the highest levels of the virus in the testes of male mice--a finding that supports clinical data indicating the virus can be sexually transmitted.


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